Impact of Pain on Lumbar Spine Functional Assessment: Are Sufficient Flexion and Extension Achieved?

疼痛对腰椎功能评估的影响：是否能实现充分的屈伸活动？

There is currently no universally accepted standard for evaluating lumbar spinal instability, and assessment criteria vary across institutions, potentially leading to inconsistent decision-making when choosing between decompression alone and decompression with fusion. To address the need for consistent and reproducible functional radiographs, we investigated the influence of pain on lumbar motion during functional radiography. Pain may limit flexion during conventional radiography, potentially underestimating instability. The HK method may help establish objective criteria and surgical planning through improved reproducibility.

目前，对于评估腰椎不稳尚无普遍接受的标准，各机构的评估标准存在差异，这可能导致在选择单纯减压术和减压融合术时决策不一致。为满足获取一致且可重复的功能位 X 线片的需求，我们研究了疼痛对功能位 X 线检查时腰椎活动的影响。在常规 X 线检查中，疼痛可能会限制腰椎前屈，从而可能低估腰椎不稳情况。HK 方法或许能通过提高可重复性来帮助制定客观标准和进行手术规划。

REF: Morita T, Tsukamoto A, Fukushi R, et al. Impact of Pain on Lumbar Spine Functional Assessment: Are Sufficient Flexion and Extension Achieved?. World Neurosurg. 2026;206:124752. doi:10.1016/j.wneu.2025.124752 PMID: 41422926

BMI and Patient-Reported Outcomes Following Spinal Surgery: A Retrospective Review

脊柱手术后的身体质量指数（BMI）与患者报告结局：一项回顾性研究

Body mass index (BMI) plays an important role in surgical outcomes following spinal fusion surgery, with increasing BMI linked to greater risk of post-operative complications. However, the relationship between BMI and long-term patient-reported outcome measures (PROMs) lacks investigation. This study aims to evaluate the association between patient BMI and PROMs in patients undergoing spinal fusion surgery. In this large ERAS-based spinal fusion cohort, elevated BMI was associated with significantly worse mean pain and disability scores but did not consistently predict clinically meaningful improvement. Recovery was more strongly influenced by time from surgery, surgical complexity, and demographic factors rather than BMI alone. These findings suggest BMI should not be used in isolation to determine postoperative expectations and support individualized perioperative optimization.

体重指数（BMI）在脊柱融合手术后的手术结果中起着重要作用，BMI升高与术后并发症风险增加有关。然而，BMI与患者长期报告结局指标（PROMs）之间的关系尚缺乏研究。本研究旨在评估接受脊柱融合手术患者的BMI与PROMs之间的关联。在这个基于加速康复外科（ERAS）的大型脊柱融合队列中，BMI升高与显著更差的平均疼痛和残疾评分相关，但并不能始终如一地预测具有临床意义的改善情况。与手术的时间间隔、手术复杂程度和人口统计学因素对康复的影响比单纯的BMI更为显著。这些发现表明，不应仅依靠BMI来设定术后预期，而应支持个体化的围手术期优化方案。

REF: Bever N, Ebada A, Liu MA, Aoun SG. BMI and Patient-Reported Outcomes Following Spinal Surgery: A Retrospective Review. World Neurosurg. 2026;206:124725. doi:10.1016/j.wneu.2025.124725 PMID: 41397665

Polymethylmethacrylate Versus Autologous Bone Flap Reconstruction After Retrosigmoid Vestibular Schwannoma Surgery: Impact on Wound Healing and Patient Satisfaction

乙状窦后前庭神经鞘瘤手术后聚甲基丙烯酸甲酯与自体骨瓣重建的比较：对伤口愈合和患者满意度的影响

Retrosigmoid repair techniques vary widely between and within institutions, complicating comparisons of patient satisfaction and complications. This study aimed to analyze patients' satisfaction with the skin flap healing process and associated symptoms, such as pain, hypoesthesia, dysesthesia, pressure, and tension, as well as to assess wound healing complications, and to evaluate both clinical and esthetic results using polymethylmethacrylate (PMMA) or autologous bone coverage following vestibular schwannoma surgery. While patient satisfaction did not differ between reconstruction methods, PMMA for bone defect coverage in vestibular schwannoma surgery may have the potential to reduce wound healing disorders compared with autologous bone.

乙状窦后修复技术在不同机构之间以及同一机构内部差异很大，这使得患者满意度和并发症的比较变得复杂。本研究旨在分析患者对皮瓣愈合过程及相关症状（如疼痛、感觉减退、感觉异常、压迫感和紧绷感）的满意度，评估伤口愈合并发症，并使用聚甲基丙烯酸甲酯（PMMA）或自体骨覆盖物评估前庭神经鞘瘤手术后的临床和美学效果。虽然不同重建方法之间患者满意度无差异，但与自体骨相比，在前庭神经鞘瘤手术中使用PMMA覆盖骨缺损可能有降低伤口愈合障碍的潜力。

REF: Khalaveh F, Busch S, Yildirim MS, et al. Polymethylmethacrylate Versus Autologous Bone Flap Reconstruction After Retrosigmoid Vestibular Schwannoma Surgery: Impact on Wound Healing and Patient Satisfaction. World Neurosurg. 2026;206:124760. doi:10.1016/j.wneu.2025.124760 PMID: 41456754

Intracavernous Aneurysms, Their Characteristics, and Rate of Growth: An Analysis of 104 Aneurysms

海绵窦内动脉瘤：其特征及生长速率——104例动脉瘤分析

Carotid cavernous aneurysms (CCAs) are rare aneurysms of the cavernous segment of the internal carotid artery. We aim to analyze the growth and characteristics of CCAs from a large single-hospital cohort. CCAs are typically small, saccular, and asymptomatic, with low rupture risk. Follow-up of medium-sized CCAs is recommended, with treatment decisions based also on growth, morphology, and clinical symptoms.

颈内动脉海绵窦段动脉瘤（CCAs）是颈内动脉海绵窦段的罕见动脉瘤。我们旨在分析来自一家大型单中心医院队列的颈内动脉海绵窦段动脉瘤的生长情况和特征。颈内动脉海绵窦段动脉瘤通常体积较小、呈囊状且无症状，破裂风险较低。建议对中等大小的颈内动脉海绵窦段动脉瘤进行随访，治疗决策还应根据其生长情况、形态和临床症状来确定。

REF: Leivo E, Dabbagh Ohadi MA, Numminen J, Niemelä M, Jahromi BR. Intracavernous Aneurysms, Their Characteristics, and Rate of Growth: An Analysis of 104 Aneurysms. World Neurosurg. 2026;206:124758. doi:10.1016/j.wneu.2025.124758 PMID: 41456752

Adverse Impact of Frailty on Postoperative Outcomes of Cervical Laminoplasty

衰弱对颈椎椎板成形术术后结局的不良影响

Although prior studies have examined the impact of frailty on surgeries for degenerative cervical conditions, these studies often involved heterogeneous sample populations in terms of surgical approaches. This study aimed to examine the impact of frailty and its severity on postoperative outcomes after cervical laminoplasty. Frailty and its severity may be associated with a higher rate of unfavorable perioperative outcomes after cervical laminoplasty. As a result, including frailty assessment in the preoperative evaluation of patients undergoing cervical laminoplasty could be beneficial for stratifying related risks.

尽管先前的研究已探讨了衰弱对退行性颈椎疾病手术的影响，但这些研究在手术方式方面的样本群体往往具有异质性。本研究旨在探讨衰弱及其严重程度对颈椎椎板成形术后预后的影响。衰弱及其严重程度可能与颈椎椎板成形术后围手术期不良预后的发生率较高有关。因此，在接受颈椎椎板成形术患者的术前评估中纳入衰弱评估可能有助于对相关风险进行分层。

REF: Shahbandi A, Ghamasaee P, Yassin Kassab AM, Shabani S. Adverse Impact of Frailty on Postoperative Outcomes of Cervical Laminoplasty. World Neurosurg. 2026;206:124776. doi:10.1016/j.wneu.2025.124776 PMID: 41485598

Analytical Insights into the Epidemiology of Glioma and Treatment Modalities

胶质瘤流行病学及治疗方式的分析性见解

Glioma is a common malignant intracranial tumor. This study investigated different treatment strategies and multiple epidemiological characteristics-including age, sex, ethnicity, and income-on the risk of developing glioblastoma and patient survival outcomes. These findings reveal the dynamic changes in the incidence pattern of glioma, the continuous improvement in survival rates, and the prognostic value of molecular characteristics and socioeconomic factors, deepening the understanding of the effects of different treatment modalities and providing a basis for clinical diagnosis and treatment strategies.

胶质瘤是一种常见的颅内恶性肿瘤。本研究探讨了不同治疗策略以及多种流行病学特征（包括年龄、性别、种族和收入）对胶质母细胞瘤发病风险和患者生存结局的影响。这些研究结果揭示了胶质瘤发病模式的动态变化、生存率的持续提高以及分子特征和社会经济因素的预后价值，加深了对不同治疗方式效果的理解，为临床诊疗策略提供了依据。

REF: Ji M, Tian D, Qi Q, et al. Analytical Insights into the Epidemiology of Glioma and Treatment Modalities. World Neurosurg. 2026;206:124757. doi:10.1016/j.wneu.2025.124757 PMID: 41456753

Percutaneous Vertebroplasty Combined with Iodine-125 Seed Implantation for Spinal Metastases with Dural Sac Compression: A Retrospective Comparative Study

经皮椎体成形术联合碘 -125 粒子植入治疗硬膜囊受压的脊柱转移瘤：一项回顾性对照研究

To evaluate the efficacy and safety of percutaneous vertebroplasty (PVP) combined with iodine-125 seed implantation versus PVP alone for spinal metastases with dural sac compression. PVP combined with interstitial iodine-125 seed implantation is a feasible, safe, and effective alternative to PVP alone. This combined approach offers superior sustained pain relief and local tumor control for patients with spinal metastases involving dural sac compression.

评估经皮椎体成形术（PVP）联合碘 - 125 粒子植入与单纯 PVP 治疗伴有硬膜囊受压的脊柱转移瘤的疗效和安全性。PVP 联合组织间碘 - 125 粒子植入是一种可行、安全且有效的替代单纯 PVP 的方法。对于伴有硬膜囊受压的脊柱转移瘤患者，这种联合治疗方法在持续缓解疼痛和局部肿瘤控制方面效果更佳。

REF: Xiao QP, Li SY. Percutaneous Vertebroplasty Combined with Iodine-125 Seed Implantation for Spinal Metastases with Dural Sac Compression: A Retrospective Comparative Study. World Neurosurg. 2026;206:124782. doi:10.1016/j.wneu.2025.124782 PMID: 41482267

Surgical Management and Outcomes of Intradural Spinal Metastases

硬膜内脊柱转移瘤的手术治疗与预后

Intradural spinal metastases are rare but clinically significant manifestations of systemic malignancies. Their management remains controversial, and evidence guiding surgical outcomes is limited. The aim of recent study is to evaluate the clinical features, surgical outcomes, and prognostic factors with intradural spinal metastases treated surgically at a single center. Surgical resection of intradural spinal metastases can offer meaningful neurological improvement and symptom relief in selected patients. GTR is associated with better outcomes, and careful preoperative selection is critical. Multidisciplinary approaches remain essential for optimizing patient care.

硬膜内脊髓转移瘤较为罕见，但却是全身恶性肿瘤具有临床意义的表现。其治疗仍存在争议，指导手术预后的证据有限。近期一项研究的目的是评估在单一中心接受手术治疗的硬膜内脊髓转移瘤患者的临床特征、手术结局和预后因素。对部分硬膜内脊髓转移瘤患者进行手术切除可显著改善神经功能并缓解症状。全切除与更好的预后相关，谨慎的术前筛选至关重要。多学科治疗方法对于优化患者治疗仍必不可少。

REF: Ozoner B, Alioglu H, Osama M, Kus Silav Z, Bozkurt B. Surgical Management and Outcomes of Intradural Spinal Metastases. World Neurosurg. 2026;206:124773. doi:10.1016/j.wneu.2025.124773 PMID: 41478374

Proposal of Brain Plasticity Index Based on Navigated Transcranial Magnetic Stimulation: Metric of Functional Displacement for Language Function

基于导航式经颅磁刺激的脑可塑性指数的提出：语言功能的功能位移指标

To identify a brain plasticity index (BPI) that accounts for the cortical variation in language function on the basis of preoperative/postoperative navigated transcranial magnetic stimulation (nTMS) mapping. Identifying a subject-specific BPI may noninvasively define functional reshaping of corticosubcortical circuits.

确定一个脑可塑性指数（BPI），该指数基于术前/术后导航式经颅磁刺激（nTMS）映射来解释语言功能的皮质变异。确定受试者特异性的BPI可以非侵入性地确定皮质 - 皮质下回路的功能重塑。

REF: Bonaudo C, Pieropan E, Caredda C, et al. Proposal of Brain Plasticity Index Based on Navigated Transcranial Magnetic Stimulation: Metric of Functional Displacement for Language Function. World Neurosurg. 2026;206:124766. doi:10.1016/j.wneu.2025.124766 PMID: 41475456