Repeated Percutaneous Kyphoplasty for Refracture of the Same Cemented Vertebral Body

同一椎体骨水泥注入后再骨折的多次经皮椎体后凸成形术

The refracture of the previously cemented vertebrae occurs rarely following percutaneous kyphoplasty (PKP). The present study was designed to assess the therapeutic efficacy of repeated PKP for refractures. Repeated PKP effectively alleviates pain and restores spinal function in patients with refractures. A minimum cement volume of 4.5 ml appears optimal for achieving significant pain relief.

经皮椎体后凸成形术（PKP）后，先前已注入骨水泥的椎体再次骨折的情况很少发生。本研究旨在评估重复PKP治疗再骨折的疗效。重复PKP能有效缓解再骨折患者的疼痛并恢复脊柱功能。骨水泥注入量至少达到4.5毫升似乎是实现显著止痛效果的最佳选择。

REF: Shao X, Zhou Z, Wang Y, et al. Repeated Percutaneous Kyphoplasty for Refracture of the Same Cemented Vertebral Body. World Neurosurg. 2025;201:124301. doi:10.1016/j.wneu.2025.124301 PMID: 40684861

Indications and Outcomes of Intracranial Bypass: A Systematic Review and Meta-Analysis

颅内搭桥手术的适应证与预后：一项系统评价和荟萃分析

This systematic review and meta-analysis aims to provide an overview of the indications, selection criteria, and outcomes of intracranial direct bypass surgery. Despite a decline in indications, intracranial bypass surgery remains a highly relevant option for the treatment of diseases such as Moyamoya vasculopathy, as a salvage option in steno-occlusive disease with hemodynamic compromise, and treatment of aneurysms not amenable to microsurgical or endovascular repair.

这项系统评价和荟萃分析旨在概述颅内直接搭桥手术的适应证、选择标准和手术结局。尽管适应证有所减少，但颅内搭桥手术仍然是治疗烟雾病等疾病的重要选择，是治疗伴有血流动力学障碍的狭窄 - 闭塞性疾病的补救手段，也是无法进行显微外科或血管内修复的动脉瘤的治疗方法。

REF: Sadigh Y, de Haan Y, Haasdijk EJ, et al. Indications and Outcomes of Intracranial Bypass: A Systematic Review and Meta-Analysis. World Neurosurg. 2025;201:124308. doi:10.1016/j.wneu.2025.124308 PMID: 40701362

Propensity Score–Matched Analysis of the Association Between Depression, Anxiety, and Patient-Reported Outcomes Following Lumbar Surgery

腰椎手术后抑郁、焦虑与患者报告结局相关性的倾向得分匹配分析

This study aims to evaluate the relationship between a diagnosis of depression or anxiety and postoperative patient-reported outcome measures (PROMs) following lumbar fusion surgery, utilizing minimal clinically important difference (MCID) thresholds and propensity score matching. Patients with preoperative depression or anxiety experienced worse postoperative outcomes following lumbar fusion. Our findings suggest that mental health may be a modifiable risk factor that influences recovery and functional benefit after lumbar spine surgery.

本研究旨在利用最小临床重要差异（MCID）阈值和倾向得分匹配，评估抑郁症或焦虑症诊断与腰椎融合手术后患者报告结局指标（PROMs）之间的关系。术前患有抑郁症或焦虑症的患者在腰椎融合手术后的预后较差。我们的研究结果表明，心理健康可能是影响腰椎手术后恢复和功能改善的一个可调节的危险因素。

REF: Ebada A, Carron CJ, Bever N, et al. Propensity Score-Matched Analysis of the Association Between Depression, Anxiety, and Patient-Reported Outcomes Following Lumbar Surgery. World Neurosurg. 2025;201:124305. doi:10.1016/j.wneu.2025.124305 PMID: 40684859

The Efficacy of Partial Cervical Corpectomy Reconstructed with Flanged Polyether Ether Ketone (PEEK) Cages in Patients with Short Segment Degenerative Cervical Myelopathy (DCM)

带翼聚醚醚酮（PEEK）椎间融合器重建的颈椎部分椎体切除术治疗短节段退变性颈椎脊髓病（DCM）的疗效

This retrospective study evaluates the efficacy and complications of partial cervical corpectomy with flanged polyether ether ketone (PEEK) cage reconstruction for short-segment degenerative cervical myelopathy (DCM). Partial cervical corpectomy reconstructed with flanged PEEK cages is a relatively comparable treatment method for short-segment DCM.

这项回顾性研究评估了采用带翼聚醚醚酮（PEEK）椎间融合器重建的颈椎部分椎体切除术治疗短节段退变性颈椎脊髓病（DCM）的疗效和并发症。采用带翼PEEK椎间融合器重建的颈椎部分椎体切除术是治疗短节段DCM的一种相对可行的治疗方法。

REF: Ha JH, Moon JE, Im SB, Jeong JH. The Efficacy of Partial Cervical Corpectomy Reconstructed with Flanged Polyether Ether Ketone (PEEK) Cages in Patients with Short Segment Degenerative Cervical Myelopathy (DCM). World Neurosurg. 2025;201:124309. doi:10.1016/j.wneu.2025.124309 PMID: 40684857

A Predictive Nomogram Model Incorporating Contrast Extravasation for Early Prediction of Postthrombectomy Malignant Cerebral Edema

纳入造影剂外渗的预测列线图模型用于早期预测取栓术后恶性脑水肿

Early prediction of malignant cerebral edema (MCE) following endovascular thrombectomy (EVT) is critical for guiding timely interventions to improve outcomes; however, existing prediction models predominantly require complex algorithms. Contrast extravasation (CE) is a novel imaging biomarker. We aimed to develop a practical nomogram incorporating CE for predicting MCE to enhance postoperative management. CE-ASPECTS is an accessible and independent predictor of MCE. The nomogram, which is composed of age, admission fasting blood glucose level, Trial of ORG 10,172 in Acute Stroke Treatment classification, occlusion site, and CE-ASPECTS, may serve as a practical tool for predicting the probability of MCE in patients with acute ischemic stroke who achieved successful recanalization after EVT.

血管内血栓切除术（EVT）后恶性脑水肿（MCE）的早期预测对于指导及时干预以改善预后至关重要；然而，现有的预测模型大多需要复杂的算法。造影剂外渗（CE）是一种新型影像学生物标志物。我们旨在开发一种纳入CE的实用列线图来预测MCE，以加强术后管理。CE-ASPECTS是MCE的一个可获取且独立的预测因素。该列线图由年龄、入院空腹血糖水平、急性卒中治疗中ORG 10172试验（TOAST）分型、闭塞部位和CE-ASPECTS组成，可作为预测EVT后成功再通的急性缺血性卒中患者发生MCE概率的实用工具。

REF: Wu H, Sun J, Xiao C, et al. A Predictive Nomogram Model Incorporating Contrast Extravasation for Early Prediction of Postthrombectomy Malignant Cerebral Edema. World Neurosurg. 2025;201:124312. doi:10.1016/j.wneu.2025.124312 PMID: 40706954

Developing Deep Learning–Based Cerebral Ventricle Auto-Segmentation System and Clinical Application for the Evaluation of Ventriculomegaly

基于深度学习的脑室自动分割系统的开发及在脑室扩大评估中的临床应用

Current methods for evaluating ventriculomegaly, particularly Evans' Index (EI), fail to accurately assess three-dimensional ventricular changes. We developed and validated an automated multiclass segmentation system for precise volumetric assessment, simultaneously segmenting 5 anatomical classes (ventricles, parenchyma, skull, skin, and hemorrhage) to support future augmented reality-guided external ventricular drainage (EVD) systems. Our comprehensive multiclass segmentation system offers a superior alternative to traditional measurements with potential for noninvasive CSF dynamics monitoring and augmented reality-guided EVD placement.

目前评估脑室扩大的方法，尤其是埃文斯指数（EI），无法准确评估脑室的三维变化。我们开发并验证了一个自动化多类别分割系统，用于精确的容积评估，该系统可同时分割5个解剖类别（脑室、实质组织、颅骨、皮肤和出血灶），以支持未来的增强现实引导下的脑室外引流（EVD）系统。我们全面的多类别分割系统为传统测量方法提供了一个更优的替代方案，具有无创监测脑脊液动力学和指导增强现实引导下EVD置管的潜力。

REF: Nam SM, Hwang JH, Kim JM, et al. Developing Deep Learning-Based Cerebral Ventricle Auto-Segmentation System and Clinical Application for the Evaluation of Ventriculomegaly. World Neurosurg. 2025;201:124300. doi:10.1016/j.wneu.2025.124300 PMID: 40712852

Development of a Predictive Model for Kummell's Disease

库梅尔病预测模型的建立

Kümmell's disease (KD) is a recognized complication of osteoporotic thoracolumbar vertebral compression fractures (OVCFs), but the risk factors for progression from OVCFs to KD remain unclear. Intraosseous vacuum cleft; Kummell's disease; Nonunion of vertebral fracture; Osteoporosis; Post-traumatic delayed vertebral collapse.

库梅尔病（KD）是骨质疏松性胸腰椎椎体压缩骨折（OVCFs）的一种已知并发症，但从OVCFs进展为KD的危险因素仍不清楚。骨内真空裂隙；库梅尔病；椎体骨折不愈合；骨质疏松症；创伤后迟发性椎体塌陷。

REF: Song Y, Zhao H, Liu S, et al. Development of a Predictive Model for Kummell's Disease. World Neurosurg. 2025;201:124293. doi:10.1016/j.wneu.2025.124293 PMID: 40681099

Dynamic versus Fixed Lumbar Spondylolisthesis: Clinical, Radiographic, and Functional Outcomes Following Transforaminal Lumbar Interbody Fusion Surgery

动态与固定性腰椎滑脱：经椎间孔腰椎椎间融合手术后的临床、影像学及功能结局

Lumbar spondylolisthesis (LS) is defined by vertebral displacement and can be categorized as dynamic or fixed based on intervertebral instability. Dynamic LS, characterized by greater mobility, may impact surgical outcomes. This study aimed to assess clinical and radiographic differences between dynamic and fixed LS in patients undergoing transforaminal lumbar interbody fusion (TLIF) and to determine an optimal cut-off for defining dynamic instability. A displacement threshold of 2.45 mm effectively differentiates dynamic from fixed LS and may support surgical decision-making. While dynamic LS presents a higher risk of postoperative reduction loss, TLIF achieves comparable functional outcomes in both LS subtypes. Further prospective studies are needed to validate these findings and optimize surgical strategies.

腰椎滑脱（LS）是根据椎体移位来定义的，根据椎间不稳情况可分为动态型和固定型。动态型腰椎滑脱的特点是活动度更大，可能会影响手术效果。本研究旨在评估接受经椎间孔腰椎椎间融合术（TLIF）的动态型和固定型腰椎滑脱患者在临床和影像学方面的差异，并确定定义动态不稳的最佳临界值。2.45毫米的移位阈值可有效区分动态型和固定型腰椎滑脱，可能有助于手术决策。虽然动态型腰椎滑脱术后复位丢失的风险更高，但TLIF在两种类型的腰椎滑脱中均可取得相当的功能预后。需要进一步的前瞻性研究来验证这些结果并优化手术策略。

REF: Zárate-Kalfópulos B, Pesantez-Mochas F, Rojo-Castillo P, et al. Dynamic versus Fixed Lumbar Spondylolisthesis: Clinical, Radiographic, and Functional Outcomes Following Transforaminal Lumbar Interbody Fusion Surgery. World Neurosurg. 2025;201:124310. doi:10.1016/j.wneu.2025.124310 PMID: 40684860

Kissing Spine and Other Imaging Predictors of Postoperative Cement Displacement Following Percutaneous Kyphoplasty: A Machine Learning Approach

吻性椎体及其他经皮椎体后凸成形术后骨水泥移位的影像学预测指标：一种机器学习方法

To investigate the risk factors associated with postoperative cement displacement following percutaneous kyphoplasty in patients with osteoporotic vertebral compression fractures and to develop predictive models for clinical risk assessment. Key predictors of cement displacement were identified, and machine learning models were developed for risk assessment. These findings can assist clinicians in identifying high-risk patients, optimizing treatment strategies, and improving patient outcomes.

探讨骨质疏松性椎体压缩骨折患者经皮椎体后凸成形术后骨水泥移位的相关危险因素，并建立用于临床风险评估的预测模型。确定了骨水泥移位的关键预测因素，并开发了用于风险评估的机器学习模型。这些研究结果可帮助临床医生识别高风险患者，优化治疗策略，改善患者预后。

REF: Zhao Y, Bo L, Qian L, et al. Kissing Spine and Other Imaging Predictors of Postoperative Cement Displacement Following Percutaneous Kyphoplasty: A Machine Learning Approach. World Neurosurg. 2025;201:124322. doi:10.1016/j.wneu.2025.124322 PMID: 40712848