Age-Dependent Risk Factors for Hemorrhagic Events in Moyamoya Disease: The Role of Collateral Vessels

烟雾病出血事件的年龄相关危险因素：侧支血管的作用

To describe profiles of collateral arteries of moyamoya disease (MMD) and analyze risk factors of cerebral hemorrhagic events. Differences in collateral arteries between adult patients with MMD and pediatric patients with MMD were observed, among which MMA acted as a predictor for cerebral hemorrhage in adult patients with MMD.

描述烟雾病（MMD）侧支动脉特征并分析脑出血事件的危险因素。观察成年和小儿MMD患者侧支动脉的差异，其中脑膜中动脉（MMA）可作为成年MMD患者脑出血的预测因素。

REF: Luo R, Liu T, Li W, Zhu C, Zhu H, Zhang Y. Age-Dependent Risk Factors for Hemorrhagic Events in Moyamoya Disease: The Role of Collateral Vessels. World Neurosurg. 2025;198:124000. doi:10.1016/j.wneu.2025.124000 PMID: 40268187

Prevalence of Nonauditory Stimulation from Auditory Brainstem Implantation

听觉脑干植入术后非听觉刺激的患病率

Auditory brainstem implants (ABIs) can be used to restore hearing in subjects with no functional auditory nerve. Not infrequently, channels on the ABI give rise to nonauditory stimulation. The aim of the present study was to explore the prevalence of side effects for different portions of the implant and to investigate the number of active channels. Side effects were reported on the ipsilateral side of the body. The most common side effect was sensory stimulation in the ipsilateral leg. Throat stimulation was most common for the horizontal-lateral portion of the implant. The number of active electrodes decreased significantly statistically over time.

听觉脑干植入物（ABIs）可用于为无功能性听神经的患者恢复听力。ABI的电极通道引发非听觉刺激的情况并不少见。本研究的目的是探究植入物不同部位副作用的发生率，并调查活跃电极通道的数量。副作用均出现在身体同侧。最常见的副作用是同侧腿部的感觉刺激。对于植入物的水平外侧部分，最常见的副作用是喉部刺激。活跃电极的数量随时间推移在统计学上显著减少。

REF: Hallin K, Rask-Andersen H. Prevalence of Nonauditory Stimulation from Auditory Brainstem Implantation. World Neurosurg. 2025;198:123992. doi:10.1016/j.wneu.2025.123992 PMID: 40274016

Trends in Cervical Spine Surgery in the United States: A National Database Analysis

美国颈椎手术趋势：一项全国性数据库分析

Anterior cervical discectomy and fusion (ACDF), posterior cervical instrumented fusion (PCF), laminectomy/foraminotomy/facetectomy (LFF), and cervical disc arthroplasty (CDA) are commonly performed cervical spine procedures. This study aims to identify the trends in cervical spine surgery on the utilization of ACDF, PCF, LFF, and CDA in the United States over the past decade. A secondary aim of this study is to describe the average reimbursements received for these interventions. ACDF has been the most popular cervical spine surgery, but its frequency is now declining. CDA is gaining popularity, particularly among younger patients. Moreover, average per-patient inflation-adjusted reimbursements have been effectively decreasing over time.

颈椎前路椎间盘切除融合术（ACDF）、颈椎后路器械融合术（PCF）、椎板切除术/椎间孔切开术/小关节切除术（LFF）和颈椎间盘置换术（CDA）是常见的颈椎手术。本研究旨在确定过去十年美国在ACDF、PCF、LFF和CDA颈椎手术使用方面的趋势。本研究的次要目的是描述这些手术的平均报销费用。ACDF一直是最受欢迎的颈椎手术，但目前其手术频次正在下降。CDA正越来越受欢迎，尤其在年轻患者中。此外，经通胀调整后的每位患者平均报销费用实际上一直在随时间下降。

REF: Ibrahim MT, Kirven JC, Kavuri V, Yu E, Singh VK. Trends in Cervical Spine Surgery in the United States: A National Database Analysis. World Neurosurg. 2025;198:123961. doi:10.1016/j.wneu.2025.123961 PMID: 40194696

Efficacy of Flow Diverter versus Stent-Assisted Coiling for Treating Small- and Medium-Sized Intracranial Wide-Neck Cystic Aneurysms

血流导向装置与支架辅助弹簧圈栓塞治疗中小型颅内宽颈囊性动脉瘤的疗效比较

To study the efficacy of a flow diverter (FD) versus stent-assisted coiling (SAC) for the treatment of small- and medium-sized intracranial wide-neck cystic aneurysms. Both FD and SAC were shown to have good safety and efficacy for treating small- and medium-sized intracranial wide-neck cystic aneurysms. However, stent-assisted embolization may be a better choice for high-risk or ruptured aneurysms.

研究血流导向装置（FD）与支架辅助弹簧圈栓塞术（SAC）治疗中小型颅内宽颈囊性动脉瘤的疗效。FD和SAC在治疗中小型颅内宽颈囊性动脉瘤方面均显示出良好的安全性和有效性。然而，对于高风险或破裂的动脉瘤，支架辅助栓塞术可能是更好的选择。

REF: Wu Z, Yao J, Lian W, Lyu H, Rao X, Zhang M. Efficacy of Flow Diverter versus Stent-Assisted Coiling for Treating Small- and Medium-Sized Intracranial Wide-Neck Cystic Aneurysms. World Neurosurg. 2025;198:123990. doi:10.1016/j.wneu.2025.123990 PMID: 40252695

Plasma Circulating Proteins and Intracranial Aneurysm Susceptibility: A Proteome-Wide Mendelian Randomization Analysis

血浆循环蛋白与颅内动脉瘤易感性：全蛋白质组孟德尔随机化分析

Intracranial aneurysms (IAs) are cerebrovascular diseases with exceptionally high mortality and disability rates. Preventing and treating IA are crucial steps toward reducing the burden of these conditions. We propose conducting a proteome Mendelian randomization study to investigate key plasma proteins that influence IA and to identify biomarkers and therapeutic targets for their prevention and treatment. Circulating protein BTD reduces the risk of IA and may serve as a key biomarker and preventive target for IA.

颅内动脉瘤（IAs）是死亡率和致残率极高的脑血管疾病。预防和治疗颅内动脉瘤是减轻这些疾病负担的关键步骤。我们提议开展一项蛋白质组孟德尔随机化研究，以探究影响颅内动脉瘤的关键血浆蛋白，并确定用于其预防和治疗的生物标志物及治疗靶点。循环蛋白生物素酶（BTD）可降低颅内动脉瘤的发病风险，有望成为颅内动脉瘤的关键生物标志物和预防靶点。

REF: Zou X, Tang Y, Zhou C. Plasma Circulating Proteins and Intracranial Aneurysm Susceptibility: A Proteome-Wide Mendelian Randomization Analysis. World Neurosurg. 2025;198:124015. doi:10.1016/j.wneu.2025.124015 PMID: 40294794

Simplified S1 Vertebral Bone Quality Score Predicts Screw Loosening in Patients with Lumbar Spondylolisthesis

简化S1椎体骨质量评分可预测腰椎滑脱患者的螺钉松动情况

Investigate whether S1 vertebral bone quality (VBQ) score serves as a viable substitute for the traditional VBQ score in predicting screw loosening in patients undergoing transforaminal lumbar interbody fusion (TLIF) for lumbar spondylolisthesis using quantitative computed tomography (QCT) as a standard reference. The elevated S1 VBQ score was identified as an independent risk factor for screw loosening and exhibits greater predictive capability compared to the traditional VBQ score in forecasting screw loosening following TLIF for lumbar spondylolisthesis.

以定量计算机断层扫描（QCT）作为标准参考，研究S1椎体骨质量（VBQ）评分是否可作为传统VBQ评分的可行替代指标，用于预测腰椎滑脱患者行经椎间孔腰椎椎间融合术（TLIF）后螺钉松动情况。较高的S1 VBQ评分被确定为螺钉松动的独立危险因素，并且在预测腰椎滑脱患者TLIF术后螺钉松动方面，其预测能力优于传统VBQ评分。

REF: Wang Y, Chen Q, Zhu C, et al. Simplified S1 Vertebral Bone Quality Score Predicts Screw Loosening in Patients with Lumbar Spondylolisthesis. World Neurosurg. 2025;198:124012. doi:10.1016/j.wneu.2025.124012 PMID: 40306411

Fully Endoscopic Microvascular Decompression for Neurovascular Compression Syndrome: Early Outcomes and Technical Note

神经血管压迫综合征的全内镜微血管减压术：早期疗效及技术要点

Neurovascular compression syndromes (NVCSs) are a series of vascular compression diseases wherein there is usually entrapment or distortion of cranial nerves due to redundant or aberrant culprit vessels. Microvascular decompression (MVD) is an effective treatment for NVCS. However, the global adoption of fully endoscopic MVD (E-MVD) remains limited. E-MVD represents a significant advancement in the treatment of NVCS, offering a promising alternative to traditional strategies.

神经血管压迫综合征（NVCS）是一系列血管压迫性疾病，通常是由于多余或异常的责任血管导致颅神经受压或扭曲。微血管减压术（MVD）是治疗NVCS的有效方法。然而，全内镜下微血管减压术（E - MVD）在全球的应用仍然有限。E - MVD是NVCS治疗领域的一项重大进展，为传统治疗策略提供了一种有前景的替代方案。

REF: Wang J, Li M, Duan Y, Zhang Z, Yu Y, Liu J. Fully Endoscopic Microvascular Decompression for Neurovascular Compression Syndrome: Early Outcomes and Technical Note. World Neurosurg. 2025;198:123995. doi:10.1016/j.wneu.2025.123995 PMID: 40252697

Evaluating the Role of Onyx Embolization in the Management of Spinal Dural Arteriovenous Fistulas: A 20-Year Single-Center Experience

评估Onyx栓塞术在脊髓硬脑膜动静脉瘘治疗中的作用：一项单中心20年经验总结

Open surgery is widely regarded as the standard treatment for spinal dural arteriovenous fistulas (SDAVFs). However, endovascular treatment (EVT) with liquid embolic agents has emerged as an alternative. While N-butyl cyanoacrylate is often preferred for its superior penetration into draining vein, this study aims to assess the effectiveness of an embolization-first strategy using Onyx, drawing on 20 years of clinical experience. The embolization-first strategy, with adjuvant surgery when necessary, can achieve outcomes nearing those of purely surgical approaches. Based on our long-term experience, EVT with Onyx can result in complete and permanent cure of SDAVF in more than 80% of cases.

开放性手术被广泛认为是脊髓硬脊膜动静脉瘘（SDAVF）的标准治疗方法。然而，使用液体栓塞剂的血管内治疗（EVT）已成为一种替代方案。虽然氰基丙烯酸正丁酯因其在引流静脉中的卓越渗透性而常被首选，但本研究旨在借鉴20年的临床经验，评估使用Onyx胶先行栓塞策略的有效性。先行栓塞策略，必要时辅以手术，可取得接近单纯手术治疗的效果。根据我们的长期经验，使用Onyx胶进行血管内治疗可使超过80%的脊髓硬脊膜动静脉瘘病例得到完全和永久性治愈。

REF: Voldřich R, Charvát F, Malík J, Netuka D. Evaluating the Role of Onyx Embolization in the Management of Spinal Dural Arteriovenous Fistulas: A 20-Year Single-Center Experience. World Neurosurg. 2025;198:124016. doi:10.1016/j.wneu.2025.124016 PMID: 40294791

Transcranial Duplex Ultrasound as an Outcome Predictor Tool in Spontaneous Intracerebral Hemorrhage

经颅双功超声作为自发性脑出血预后预测工具

To assess the usefulness of transcranial color-coded duplex (TCCD) ultrasound for monitoring intracerebral hemorrhage (ICH) and to analyze its prognostic predictive performance. TCCD-ICH volume and MLS could be used as predictive markers for dependency and mortality at three months, respectively. TCCD is a useful tool for monitoring patients with supratentorial ICH; however, these findings should be confirmed with larger studies.

评估经颅彩色编码双功超声（TCCD）监测脑出血（ICH）的实用性，并分析其预后预测效能。TCCD测量的脑出血体积和中线移位（MLS）可分别作为3个月时患者致残和死亡的预测指标。TCCD是监测幕上脑出血患者的有用工具；然而，这些研究结果尚需更大规模的研究加以证实。

REF: Pastor-Yvorra S, Dahl-Cruz F, Ramírez-Torres M, et al. Transcranial Duplex Ultrasound as an Outcome Predictor Tool in Spontaneous Intracerebral Hemorrhage. World Neurosurg. 2025;198:124010. doi:10.1016/j.wneu.2025.124010 PMID: 40288527