Association of T1-weighted hyperintensity with timing of peak bilirubin levels in neonates with hyperbilirubinemia

高胆红素血症新生儿T1加权像高信号与胆红素峰值出现时间的相关性

This study aims to investigate the association between T1-weighted hyperintensity and the timing of peak bilirubin levels in neonates with hyperbilirubinemia. The time interval between MRI and peak bilirubin levels, as well as peak TSB levels, affected T1-weighted hyperintensity of GP in neonates with hyperbilirubinemia. Findings here would benefit the selection of proper timing for MRI examinations.

本研究旨在探讨高胆红素血症新生儿T1加权像高信号与胆红素峰值出现时间的关联。高胆红素血症新生儿的磁共振成像（MRI）检查时间与胆红素峰值出现时间的间隔以及总血清胆红素（TSB）峰值水平会影响苍白球（GP）的T1加权像高信号。本研究结果将有助于选择合适的MRI检查时机。

REF: Wang R, Tian H, Ren Z, et al. Association of T1-weighted hyperintensity with timing of peak bilirubin levels in neonates with hyperbilirubinemia. Neuroradiology. Published online June 30, 2025. doi:10.1007/s00234-025-03690-2 PMID: 40586872

Are isolated linear fractures over major dural venous sinuses a risk factor for sinus thrombosis in mild TBI?

在轻度创伤性脑损伤中，主要硬脑膜静脉窦上方的孤立性线性骨折是否是窦血栓形成的危险因素？

Cerebral venous sinus thrombosis (CVST) can increase intracranial pressure and cause secondary brain injury. There is uncertainty in the literature regarding the risk of traumatic CVST (tCVST) following fractures over a major sinus, the need and timing for venous imaging, and treatment. The current study aims to review our experience with tCVST when treating patients with isolated linear fractures over the major sinuses. Amongst patients with mild, isolated, blunt traumatic head injury, with fractures traversing major dural venous sinus, true CVST may be over-diagnosed, with some of the lesions being local epidural hematomas mimicking CVST. The outcome of CVST was excellent, whether or not they were treated with anti-thrombotic medications.

脑静脉窦血栓形成（CVST）可导致颅内压升高并引起继发性脑损伤。文献中对于主要静脉窦上方骨折后发生创伤性脑静脉窦血栓形成（tCVST）的风险、静脉成像的必要性和时机以及治疗方法尚无定论。本研究旨在回顾我们治疗主要静脉窦上方单纯线性骨折患者时处理tCVST的经验。在轻度、单纯性钝性颅脑创伤患者中，对于骨折线横跨主要硬脑膜静脉窦的情况，可能存在对真正CVST的过度诊断，部分病变实际上是局部硬膜外血肿，易被误诊为CVST。无论是否使用抗血栓药物治疗，CVST患者的预后都很好。

REF: Gabay S, Dunetz G, Bergman L, Niry D, Roth J. Are isolated linear fractures over major dural venous sinuses a risk factor for sinus thrombosis in mild TBI?. Neuroradiology. Published online June 23, 2025. doi:10.1007/s00234-025-03670-6 PMID: 40549183

A bicentric study on the prevalence and clinical relevance of subarachnoid hyperdensities on flat-detector CT after thrombectomy in dominant, co-dominant, and non-dominant M2 occlusions

一项关于优势型、共优势型和非优势型M2段闭塞取栓术后平板探测器CT显示蛛网膜下腔高密度影的患病率及其临床相关性的双中心研究

Subarachnoid hyperdensities (SH) on flat-detector CT (FDCT) after mechanical thrombectomy (MT) are associated with less favorable clinical outcomes. We aimed to further elucidate the prevalence and clinical significance of SH following MT, especially in patients with dominant, co- and non-dominant M2 occlusions. SH are common after MT, especially in M2 occlusions. They are associated with poorer functional outcomes in patients with co- and non-dominant M2 occlusions and higher numbers of device passes (>3).

机械取栓术（MT）后平板探测器 CT（FDCT）显示的蛛网膜下腔高密度影（SH）与较差的临床结局相关。我们旨在进一步阐明 MT 后 SH 的发生率及其临床意义，尤其是在优势侧、双侧及非优势侧 M2 段闭塞患者中。SH 在 MT 后很常见，尤其是在 M2 段闭塞患者中。在双侧及非优势侧 M2 段闭塞患者以及器械通过次数较多（>3 次）的患者中，SH 与较差的功能结局相关。

REF: Zidan M, Serrallach BL, Branca M, et al. A bicentric study on the prevalence and clinical relevance of subarachnoid hyperdensities on flat-detector CT after thrombectomy in dominant, co-dominant, and non-dominant M2 occlusions. Neuroradiology. Published online June 19, 2025. doi:10.1007/s00234-025-03679-x PMID: 40536672

Quantitative plaque characteristics based on 3D high-resolution vessel wall imaging predict long-term recurrence in intracranial atherosclerotic stroke

基于三维高分辨率血管壁成像的斑块定量特征可预测颅内动脉粥样硬化性卒中的长期复发情况

To investigate the association between plaque characteristics observed using three-dimensional high-resolution magnetic resonance vessel wall imaging (3D HRMR-VWI) and the recurrence of ipsilateral stroke in patients diagnosed with symptomatic intracranial atherosclerotic stenotic disease. Plaque burden and enhancement ratio were independent predictors of recurrent symptomatic intracranial atherosclerotic stroke. Incorporating age with plaque characteristics enhanced long-term stroke recurrence risk prediction.

探讨应用三维高分辨率磁共振血管壁成像（3D HRMR - VWI）观察到的斑块特征与确诊为症状性颅内动脉粥样硬化狭窄疾病患者同侧卒中复发之间的关联。斑块负荷和强化率是症状性颅内动脉粥样硬化性卒中复发的独立预测因素。将年龄与斑块特征相结合可提高对卒中长期复发风险的预测能力。

REF: Zhao Y, Yang J, Dai Y, et al. Quantitative plaque characteristics based on 3D high-resolution vessel wall imaging predict long-term recurrence in intracranial atherosclerotic stroke. Neuroradiology. Published online June 19, 2025. doi:10.1007/s00234-025-03642-w PMID: 40536671

A low apparent diffusion coefficient value is associated with hemorrhagic transformation following endovascular treatment for a large ischemic core

低表观扩散系数值与大缺血核心血管内治疗后的出血转化相关。

Endovascular treatment (EVT) for large ischemic stroke is associated with a risk of hemorrhagic transformation (HT). The severity of ischemic stress can be assessed using the apparent diffusion coefficient (ADC), with a high ADC indicating viability. This study aimed to examine whether a low ADC is associated with HT following EVT, based on a low Alberta Stroke Program Early Computed Tomography Score (ASPECTS) and diffusion-weighted imaging (DWI). A low peak ADC was associated with HT after EVT for a large ischemic core. The threshold of the peak ADC that resulted in HT was < 480 × 10-6 mm2/s. These results suggest that evaluating the ischemic core is necessary to confirm EVT.

大缺血性卒中的血管内治疗（EVT）存在出血转化（HT）风险。可使用表观扩散系数（ADC）评估缺血应激的严重程度，ADC值高表明组织具有活性。本研究旨在基于低阿尔伯塔卒中项目早期计算机断层扫描评分（ASPECTS）和弥散加权成像（DWI），探讨低ADC值是否与EVT后的HT相关。对于大缺血核心，低峰值ADC值与EVT后的HT相关。导致HT的峰值ADC阈值为< 480 × 10⁻⁶ mm²/s。这些结果表明，评估缺血核心对于确定是否进行EVT是必要的。

REF: Umemura T, Tanaka Y, Kurokawa T, et al. A low apparent diffusion coefficient value is associated with hemorrhagic transformation following endovascular treatment for a large ischemic core. Neuroradiology. Published online June 18, 2025. doi:10.1007/s00234-025-03682-2 PMID: 40531215

Prevalence of suboccipital and intradural vertebral artery variants: a systematic review with meta-analysis

枕下和硬膜内椎动脉变异的患病率：一项系统评价与荟萃分析

The current systematic review, along with a meta-analysis, aims to present and calculate the pooled prevalence of the morphological variants of the vertebral artery (VA) within the suboccipital (V3) and intradural (V4) segments. Magnetic resonance or computed tomography angiographies can accurately illustrate the distal VA’s diverse anatomical configurations. Specific variants hold substantial clinical significance, as they are correlated with posterior circulation cerebrovascular incidents and may complicate posterior approaches to the craniocervical region.

当前的系统评价以及荟萃分析旨在呈现并计算枕下（V3）段和硬膜内（V4）段椎动脉（VA）形态变异的合并患病率。磁共振或计算机断层血管造影能够准确显示椎动脉远端的各种解剖结构。特定的变异具有重要的临床意义，因为它们与后循环脑血管事件相关，并且可能使颅颈区域的后路手术操作变得复杂。

REF: Triantafyllou G, Papadopoulos-Manoralarakis P, Tudose RC, Rusu MC, Tsakotos G, Piagkou M. Prevalence of suboccipital and intradural vertebral artery variants: a systematic review with meta-analysis. Neuroradiology. Published online June 16, 2025. doi:10.1007/s00234-025-03674-2 PMID: 40522487

Safety and efficacy of the Woven EndoBridge (WEB) device in ruptured intracranial aneurysms: a systematic review and updated meta-analysis

编织型血管内封堵器（WEB）治疗破裂颅内动脉瘤的安全性和有效性：系统评价与最新荟萃分析

The Woven EndoBridge (WEB; Terumo) device has gained increasing recognition for treating ruptured intracranial aneurysms (RIAs) due to its ability to disrupt flow with a single implant, avoiding long-term dual antiplatelet therapy. Despite multiple studies, a comprehensive synthesis of recent evidence remains lacking. This study addresses this gap through a systematic review and meta-analysis evaluating the WEB device's safety and efficacy in RIA management. Our findings indicate that the WEB device is a safe and effective treatment for RIAs, offering high rates of adequate occlusion, good functional outcomes, and low complication rates. This evidence reaffirms the WEB device's safety and efficacy, supporting its wider adoption in clinical use.

编织型血管内封堵器（Woven EndoBridge，WEB；泰尔茂公司）因其可通过单次植入实现血流阻断，避免长期双重抗血小板治疗，在治疗破裂颅内动脉瘤（RIAs）方面日益受到认可。尽管已有多项研究，但仍缺乏对近期证据的全面综合分析。本研究通过系统评价和荟萃分析来填补这一空白，评估WEB装置在破裂颅内动脉瘤管理中的安全性和有效性。我们的研究结果表明，WEB装置是治疗破裂颅内动脉瘤的一种安全有效的方法，具有较高的充分闭塞率、良好的功能预后和较低的并发症发生率。这一证据再次证实了WEB装置的安全性和有效性，支持其在临床中更广泛地应用。

REF: Ferreira MY, Cardoso LJC, Scarramal JPL, et al. Safety and efficacy of the Woven EndoBridge (WEB) device in ruptured intracranial aneurysms: a systematic review and updated meta-analysis. Neuroradiology. Published online June 16, 2025. doi:10.1007/s00234-025-03677-z PMID: 40522486

Percutaneous management of pyogenic spondylodiscitis using absorbable antibiotic carrier (STIMULAN®): preliminary results from a single-center study

使用可吸收抗生素载体（STIMULAN®）经皮治疗化脓性脊柱椎间盘炎：单中心研究的初步结果

This study evaluates the feasibility of using a fully resorbable antibiotic carrier (STIMULAN®, Rapid Cure, Biocomposites Ltd, UK) for the targeted treatment of spondylodiscitis (SD) through percutaneous injection directly into the infection site. The findings suggest that STIMULAN® enables safe, effective local antibiotic delivery in SD, with meaningful clinical and biomarker improvements. Nonetheless, larger multicenter studies are needed to validate these preliminary results and assess long-term efficacy.

本研究评估了使用完全可吸收的抗生素载体（STIMULAN®，快速固化型，英国生物复合材料有限公司）通过经皮直接注射至感染部位来靶向治疗脊椎椎间盘炎（SD）的可行性。研究结果表明，STIMULAN® 能够在 SD 治疗中安全、有效地进行局部抗生素递送，并使临床症状和生物标志物得到显著改善。尽管如此，仍需开展更大规模的多中心研究来验证这些初步结果并评估长期疗效。

REF: Bellini M, Hirsch JA, Marcia S, et al. Percutaneous management of pyogenic spondylodiscitis using absorbable antibiotic carrier (STIMULAN®): preliminary results from a single-center study. Neuroradiology. Published online June 14, 2025. doi:10.1007/s00234-025-03676-0 PMID: 40515821

The cochlear basal turn as a very preserved region in cochlear hypoplasias: radiological and embryological considerations from a cohort of 125 patients

耳蜗基底转在耳蜗发育不全中是一个保存完好的区域：来自125例患者队列的放射学和胚胎学考量

A distinct form of cochlear hypoplasia, characterized by the preservation of the first half of the basal turn with hypoplastic and anteriorly displaced upper turns, was historically associated with branchio-oto-renal (BOR) syndrome, but can also occur in other genetic, syndromic and non-syndromic causes of hearing loss. This study aims to describe this phenotype with relative preservation of the basal turn, particularly its first half, in a significant proportion of cochlear hypoplasia cases due to different causes. Preservation of the first half of the basal turn suggests developmental arrest between 50 and 54 days of gestation, and is common across genetic and non-genetic conditions of cochlear hypoplasia. Frequent facial nerve anomalies may complicate cochlear implantation. Integrating imaging with embryological insights supports the need for refined, developmentally-based classification systems.

一种独特的耳蜗发育不全形式，其特征是基底转的前半部分得以保留，而上部转发育不全且向前移位，在历史上与鳃耳肾（BOR）综合征相关，但也可能由其他导致听力损失的遗传性、综合征性和非综合征性原因引起。本研究旨在描述在因不同原因导致的大量耳蜗发育不全病例中，基底转尤其是其前半部分相对保留的这种表型。基底转前半部分的保留提示妊娠50至54天之间发生了发育停滞，并且在遗传性和非遗传性耳蜗发育不全病症中都很常见。频繁出现的面神经异常可能会使人工耳蜗植入手术变得复杂。将影像学检查与胚胎学见解相结合，凸显了需要完善基于发育的分类系统。

REF: Messina A, Clement E, De Bakker B, et al. The cochlear basal turn as a very preserved region in cochlear hypoplasias: radiological and embryological considerations from a cohort of 125 patients. Neuroradiology. Published online June 14, 2025. doi:10.1007/s00234-025-03671-5 PMID: 40515822