Short-Term Outcomes of a Novel Non-Screw Based Expandable Posterior Interbody Fusion Cage

新型非螺钉可扩张后路椎间融合器的短期疗效

Lumbar interbody fusion is a well-established surgical technique for treating various lumbar degenerative pathologies. Expandable cages have been introduced to allow for insertion via the confined access and to improve disc height restoration, although concerns about the stability of the screw-based cages in the expanded state remain a concern. This study aims to evaluate the short-term clinical and radiographic outcomes of a novel nonscrew-based expandable transforaminal lumbar interbody fusion cage. The novel nonscrew-based expandable cage effectively restored and maintained disc height with a low incidence of complications, suggesting it as a safe and effective alternative for lumbar interbody fusion. Further long-term studies are needed to confirm its efficacy and safety.

腰椎椎间融合术是一种成熟的手术技术，用于治疗各种腰椎退行性疾病。已经引入了可扩展的保持架，以允许通过受限的入口插入并改善椎间盘高度恢复，尽管对基于螺钉的保持架在扩展状态下的稳定性的担忧仍然是一个问题。本研究旨在评估一种新型的基于非螺钉的可膨胀经椎间孔腰椎椎间融合器的短期临床和影像学结果。新型的非螺钉式可扩张椎间融合器可有效恢复和维持椎间盘高度，并发症发生率低，这表明它是腰椎椎间融合术的一种安全有效的替代方法。需要进一步的长期研究来证实其有效性和安全性。

REF: Guven AE, Zadeh AT, Chiapparelli E, et al. Short-Term Outcomes of a Novel Non-Screw Based Expandable Posterior Interbody Fusion Cage. World Neurosurg. 2025;194:123530. doi:10.1016/j.wneu.2024.11.113 PMID: 39631670

Double Crush Syndrome in the Lower Extremity: Simultaneous L5 Radiculopathy and Common Peroneal Nerve Compression

下肢双挤压综合征: 同时发生的L5神经根病和腓总神经压迫

Double crush syndrome (DCS) is defined as multiple sites of compression along a single nerve. The combination of a compressive proximal lesion in the lumbar spine and a distal common peroneal nerve entrapment may result in compound nerve dysfunction. This is the first series to report DCS with two active points of compression in the lumbar spine and lower extremity based on EMG and imaging findings. Common peroneal nerve decompression was found to improve average dorsiflexion strength.

双挤压综合征 (DCS) 被定义为沿着单个神经的多个压迫部位。腰椎近端压缩性病变和腓总神经远端卡压的结合可能导致复合神经功能障碍。这是第一个根据EMG和影像学发现报告在腰椎和下肢有两个有效压缩点的DCS的系列。发现腓总神经减压术可改善平均背屈强度。

REF: Santangelo G, Singh A, Catanzaro M, et al. Double Crush Syndrome in the Lower Extremity: Simultaneous L5 Radiculopathy and Common Peroneal Nerve Compression. World Neurosurg. 2025;194:123502. doi:10.1016/j.wneu.2024.11.085 PMID: 39586462

Evaluation of the Therapeutic Effect of Decompression with or without Fusion on Lumbar Spinal Stenosis Caused by Degenerative Lumbar Spondylolisthesis: A Systematic Review and Meta-Analysis

减压与不融合治疗退行性腰椎滑脱所致腰椎管狭窄症疗效的系统综述和Meta分析

As a common clinical disease, lumbar spinal stenosis (LSS) is currently the preferred surgical treatment, and there are various opinions. We conducted a study on whether fusion should be performed simultaneously with decompression for LSS caused by low-grade degenerative lumbar spondylolisthesis and compared the efficacy and safety of the 2 surgeries. In this article, decompression alone has shorter surgical and hospitalization time and less intraoperative bleeding compared to decompression plus fusion. And there was no significant difference in pain score and disability index between the 2 surgeries during follow-up. Therefore, we can say that for patients with LSS caused by low-grade lumbar spondylolisthesis, decompression alone is not inferior to decompression plus fusion.

腰椎管狭窄症 (LSS) 作为临床常见病，是目前首选的手术治疗方法，众说纷纭。我们对低级别退变性腰椎滑脱引起的LSS是否应同时进行融合和减压进行了研究，并比较了两种手术的有效性和安全性。在本文中，与减压加融合术相比，单独减压术的手术和住院时间更短，术中出血更少。随访期间，两种手术的疼痛评分和功能障碍指数差异无统计学意义。因此，我们可以说，对于由低度腰椎滑脱引起的LSS患者，单纯减压不逊于减压加融合。

REF: Guo J, Fan Y, Diao H, et al. Evaluation of the Therapeutic Effect of Decompression with or without Fusion on Lumbar Spinal Stenosis Caused by Degenerative Lumbar Spondylolisthesis: A Systematic Review and Meta-Analysis. World Neurosurg. 2025;194:123512. doi:10.1016/j.wneu.2024.11.095 PMID: 39603451

Outcomes of Oberlin Transfer in Elderly Patients: A Case Series

老年患者Oberlin转移的结果: 病例系列

A case series analysis was performed of upper brachial plexus injuries (BPIs) from low-impact trauma in patients ≥60 years old to assess the effectiveness of nerve transfers, particularly the Oberlin technique, in restoring elbow flexion and to refine clinical decision making for managing traumatic BPIs in this age group. Positive outcomes were achieved with the Oberlin technique in patients >60 with upper BPIs from low-energy trauma. However, delayed surgery, significant atrophy, and low testosterone levels may affect results. Evaluation of each patient's medical history is crucial before performing this procedure.

对 ≥ 60岁患者的低冲击创伤引起的上臂丛神经损伤 (bpi) 进行了病例系列分析，以评估神经转移，尤其是Oberlin技术在恢复肘关节屈曲方面的有效性，并完善了临床决策。在这个年龄组中管理创伤性bpi。Oberlin技术在60岁以上低能量创伤的上bpi患者中取得了积极的结果。然而，手术延迟、明显萎缩和睾酮水平低可能会影响结果。在执行此程序之前，评估每位患者的病史至关重要。

REF: Guedes F, Llorian E, Henriques VM, Haikal N, Sanches GE. Outcomes of Oberlin Transfer in Elderly Patients: A Case Series. World Neurosurg. 2025;194:123510. doi:10.1016/j.wneu.2024.11.093 PMID: 39603458

Aneurysmal Subarachnoid Hemorrhage; Early Surgery; Neurosurgeons Experience; Patient Outcome

动脉瘤性蛛网膜下腔出血; 早期手术; 神经外科经验; 患者预后

This study examined the impact of neurosurgeons' experience on surgical timing and outcomes in aneurysmal subarachnoid hemorrhage (aSAH) and questioned the adherence to early surgery as recommended by recent guidelines. Experienced neurosurgeons tend to favor delayed intervention for aSAH surgery. While experience positively influences early outcomes, its impact on long-term results is less significant. Future studies could lead to improvements in neurosurgical practices.

这项研究检查了神经外科医生的经验对动脉瘤性蛛网膜下腔出血 (aSAH) 的手术时机和结果的影响，并质疑了最近指南推荐的早期手术的依从性。经验丰富的神经外科医生倾向于对aSAH手术进行延迟干预。虽然经验对早期结果有积极影响，但对长期结果的影响不那么显著。未来的研究可能会导致神经外科实践的改善。

REF: Elbir Ç, Ülkü G, Dolgun H, Demirtaş OK, Türkoğlu ME. Aneurysmal Subarachnoid Hemorrhage; Early Surgery; Neurosurgeons Experience; Patient Outcome. World Neurosurg. 2025;194:123509. doi:10.1016/j.wneu.2024.11.092 PMID: 39622284

Opiate Use Patterns Following Surgery for High Grade Glioma

高级别神经胶质瘤手术后的阿片类药物使用模式

Opiate drugs are commonly prescribed for postoperative pain relief following craniotomy. The aim of this study was to assess opiate use in patients undergoing craniotomy for high-grade glioma and to identify risk factors contributing to prolonged opiate use. Postoperative opiate use in this cohort is modest. Increased opiate use is associated with comorbidities known to modulate pain perception. Prospective studies should be conducted to provide more robust data.

阿片类药物通常用于开颅术后的术后疼痛缓解。这项研究的目的是评估因高级别神经胶质瘤而接受开颅手术的患者的阿片类药物使用情况，并确定导致长期使用阿片类药物的危险因素。在这个队列中，术后阿片类药物的使用是适度的。阿片类药物使用增加与已知调节疼痛感知的合并症有关。应进行前瞻性研究以提供更可靠的数据。

REF: Hey G, Deleyrolle P, Dagra A, et al. Opiate Use Patterns Following Surgery for High Grade Glioma. World Neurosurg. 2025;194:123507. doi:10.1016/j.wneu.2024.11.090 PMID: 39603455

Comprehensive Diagnostic Value of Vertebral Bone Quality Scores and Paravertebral Muscle Quality Parameters in Osteoporotic Vertebral Fractures

椎体骨质量评分与椎旁肌质量参数对骨质疏松性椎体骨折的综合诊断价值

Both vertebral bone quality (VBQ) scores and paravertebral muscle quality can predict osteoporotic vertebral fractures (OVFs). This study aimed to compare the diagnostic value of opportunistic VBQ scores and sarcopenia for OVF and to determine if their combined use could enhance diagnostic efficacy. The predictive value of MF CSA in anticipating OVF was marginally superior to that of VBQ and MF DFF. Furthermore, the concurrent utilization of VBQ and MF CSA substantially enhanced the diagnostic accuracy of OVF. Considering that both VBQ and MF CSA can be opportunistically obtained during routine examinations, individuals with a VBQ ≥3.46 and MF CSA ≤11.83 cm2 should be categorized as high risk for OVF, warranting timely preventive measures.

椎体骨质量 (VBQ) 评分和椎旁肌质量均可预测骨质疏松性椎体骨折 (OVFs)。这项研究旨在比较机会性VBQ评分和肌肉减少症对OVF的诊断价值，并确定它们的联合使用是否可以增强诊断功效。MF CSA对预测OVF的预测价值略高于VBQ和MF DFF。此外，VBQ和MF CSA的同时使用大大提高了OVF的诊断准确性。考虑到在常规检查中可以机会性地获得VBQ和MF CSA，因此VBQ ≥ 3.46且MF CSA ≤ 11.83平方厘米的个体应归类为OVF的高风险，因此应及时采取预防措施。

REF: Wang S, Liu L, Liu H, et al. Comprehensive Diagnostic Value of Vertebral Bone Quality Scores and Paravertebral Muscle Quality Parameters in Osteoporotic Vertebral Fractures. World Neurosurg. 2025;194:123503. doi:10.1016/j.wneu.2024.11.086 PMID: 39603452

The Effectiveness and Safety of Chemoprophylaxis in the Surgical Management of Spinal Trauma: A Systematic Review and Meta-Analysis

脊柱创伤手术中化学预防的有效性和安全性: 系统综述和荟萃分析

Chemoprophylaxis for preventing venous thromboembolism (VTE) in spine surgery is debated due to effectiveness and safety concerns. Guidelines lack consensus on regimens and timing for spinal trauma. We examined chemoprophylaxis in spine trauma surgery to further guide surgeon decision-making. No significant association was found between chemoprophylaxis use or timing and VTE risk after spine trauma surgery, though this finding may be underpowered. Chemoprophylaxis did not appear to significantly increase postoperative bleeding.

由于有效性和安全性方面的考虑，在脊柱手术中预防静脉血栓栓塞 (VTE) 的化学预防存在争议。指南对脊柱创伤的治疗方案和时机缺乏共识。我们研究了脊柱创伤手术中的化学预防，以进一步指导外科医生的决策。脊柱创伤手术后，化学预防的使用或时机与VTE风险之间没有发现显着关联，尽管这一发现可能不足。化学预防似乎并未显着增加术后出血。

REF: Anaspure OS, Baumann AN, Fiorentino A, et al. The Effectiveness and Safety of Chemoprophylaxis in the Surgical Management of Spinal Trauma: A Systematic Review and Meta-Analysis. World Neurosurg. 2025;194:123554. doi:10.1016/j.wneu.2024.12.013 PMID: 39674320

Dexmedetomidine is Associated with Reduced In-Hospital Mortality Risk of Patients with Subarachnoid Hemorrhage Undergoing Surgery

右美托咪定与蛛网膜下腔出血手术患者院内死亡风险降低相关

Subarachnoid hemorrhage (SAH) is a severe neurologic event with high mortality. The choice of sedatives in SAH management may influence patient outcomes. This study aimed to investigate the association between sedatives and in-hospital mortality among patients with SAH. Dexmedetomidine is associated with significantly lower in-hospital mortality in patients with SAH. These findings underscore the importance of sedative choice for patients with SAH, suggesting that dexmedetomidine could enhance patient outcomes.

蛛网膜下腔出血 (SAH) 是一种严重的神经系统事件，死亡率高。SAH管理中镇静剂的选择可能会影响患者的预后。本研究旨在探讨SAH患者中镇静剂与院内死亡率之间的关系。右美托咪定可显著降低SAH患者的住院死亡率。这些发现强调了SAH患者镇静选择的重要性，表明右美托咪定可以增强患者的预后。

REF: Liu Y, Peng J, Zhang YH, Liu HT. Dexmedetomidine is Associated with Reduced In-Hospital Mortality Risk of Patients with Subarachnoid Hemorrhage Undergoing Surgery. World Neurosurg. 2025;194:123539. doi:10.1016/j.wneu.2024.11.122 PMID: 39645076